Home Uncategorized Refined Glycerine

Refined Glycerine

Purity:     99.5% USP Grade

HS Code:  29054500

CAS No:    56-81-5



Refined glycerine, or glycerol, has a wide range of applications in the food, pharmaceutical, medical and personal care industries, as well as a variety of industrial and scientific uses.

In foods and beverages, glycerol serves as a humectant, solvent, and artificial sweetener. It is also used as filler in commercially prepared low-fat foods, and as a thickening agent in liqueurs.

Glycerol is used in medical, pharmaceutical and personal care preparations mainly as a means of improving smoothness, providing lubrication, and as a humectant. It is found in allergen immunotherapies, cough syrups, elixirs and expectorants, toothpaste, mouthwashes, skin care products, shaving cream, hair care products, glycerin soaps and water-based personal lubricants. Nitroglycerin is the most commonplace treatment for chronic angina, the chest pain of heart disease.

Topical pure or nearly pure glycerol is an effective treatment for psoriasis, burns, bites, cuts, rashes, bedsores, and calluses. It can be used orally to eliminate halitosis, as it is a contact bacterial desiccant. The same property makes it very helpful with periodontal disease; it penetrates biofilm quickly and eliminates bacterial colonies.

In surface science, glycerol is shown to reduce the coefficient of friction of polymer-coated surfaces by several orders of magnitude. It is also used as an alcohol-free alternative to ethanol as a solvent in preparing herbal extractions.

Glycerol is used to produce nitroglycerin, or glyceryl tinitrate (GTN), which is an essential ingredient of smokeless gunpowder and various explosives such as dynamite, gelignite, and propellants like cordite.

Technical Parameters

Description Method Value
Aspect @25 C0 Visual Clear and Viscous
Specific gravity, g/cm3 ASTM D4052 1.249 – 1.270
Glycerol content – wet basis, % mass EP 7th Ed. / USP 38 99.5 min
Glycerol content – dry basis, % mass EP 7th Ed. / USP 38 99.7 min
Water content, % mass ASTM E203 0.5 max
Color, APHA ASTM D1209 10 max
Color USP 40 confers
Melting point / Freezing Point, C0 18
Initial Boiling Point and Boiling Range, C0 290 (760 mmHg)
Flash Point, C0 160 min (closed cup)
Chlorides, ppm EP 7th Ed. / USP 38 10 max
Sulfates, ppm EP 7th Ed. / USP 38 20 max
Halogenated compounds, ppm EP 7th Ed. / USP 38 30 max
Residue on Ignition, % mass EP 7th Ed. / USP 38 0.01 max
Related compounds, % mass EP 7th Ed. / USP 38 0.1 max
Acidity or alkalinity, mL NaOH 0.1 M EP 7th Ed. / USP 38 0.2 max
Refractive index (20 C0) USP 40 1.470 – 1.475
Fatty acid and Esters, mL NaOH 0.5 M USP 40 1 max
Aldehydes, ppm EP 7th Ed. / USP 38 10 max
Diethyl glycol, % mass USP 40 0.1 max
Ethylene glycol, % mass USP 40 0.1 max
Identification A,B,C USP 40 confers
Volatile Organic Impurities, % mass USP 32 0.1 max
Residual Solvents–Alcohol (Methanol), % mass USP 40 0.3 max
Chloroform, ppm USP 32 60 max
Methylene Chloride, ppm USP 32 600 max
Trichloroethylene, ppm USP 32 80 max
1,4 Dioxane USP 32 380 max
Acid Value, mg KOH/g EP 7th Ed. / USP 38 0.1 max
Heavy Metals, ppm EP 7th Ed. / USP 38 5 max
Yeast and Molds, UFC/g EP 7th Ed. / USP 38 100 max
Total Count of Heterotrophic Bacteria, UFC/g EP 7th Ed. / USP 38 100 max
Staphylococcus Aureaus EP 7th Ed. / USP 38 Absent in 1.0 g
Gram Negative Bacilli EP 7th Ed. / USP 38 Absent in 1.0 g
Salmonella sp AOAC 2011.03 Absent 25.0 g

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